This study aims to investigate factors contributing to the failure of fresh graduates at their first workplace with qualitative research method. The core purpose of this study is to explore job mismatches, any existing gap between business students’ skills/competences provided by college of businesses and the needs of the employers. A semi-structured interview protocol was used in this study to find out the factors. In-depth interviews were conducted with a sample of 13 from Human Resource Managers and 13 fresh graduates from well-known Pharma organizations in Islamabad and Rawalpindi. The findings show that there are job mismatches which include education, qualification, specialization and interest mismatches towards job. Furthermore there are few specific soft and hard skills which is the requirement of employers. Moreover, employers and business educators differ on the relative importance of these skills. While employers emphasize the importance of the soft skills, business educators emphasize the importance of the hard skills. In addition to these finding, there are factors which are pertaining to organizations, educational institutions and society, which are the reasons of failure of fresh graduates. Supervisor:- Ms. Mariam Mohsin