The purpose of the study is to discuss the determinants of non communicable diseases at macro level in high, middle and low income countries through panel data which has incorporated 34 countries disaggregated on the basis of GNI (Gross National Income) per capita through ‘Atlas Method’ with a time of four years (with an average of 5 years each) that is: 2000, 2005, 2010 and 2015. The findings of the study shows that variables such as GDP and secondary school education when increase, they tend to decrease the Non communicable diseases, (i.e. cardiovascular disease, chronic respiratory disease, diabetes and cancers) whereas the labor force participation and health expenditure when increase they increase non communicable diseases. The study concludes that countries with higher level of incomes have less vulnerability to non communicable diseases and they can better protect themselves against such diseases and hence their macro variables have a positive impact on non communicable diseases. Supervisor:- Dr. Mahmood Khalid