The impression of primary climatic variables (temperature and precipitation) and three others like fertilizer, water and technology on crop output in two Pakistani agro-ecological zones is estimated in this study. Wheat and rice were chosen as the crops. The study employed fixed effect model approaches and panel data from 1991 to 2020. The findings demonstrated that due to changes in climate conditions, the effect of climatic variables on crop output differed among agro climatic zones. Precipitation and temperature were the most important factors of crop productivity across Pakistan’s agro-climatic zones. Temperature has a detrimental influence on wheat, while precipitation has an adverse effect on wheat produce in the long run in agro-ecological terms. Rice productivity has been impacted more by precipitation as the results are insignificant but there are alternatives for precipitation which can fulfill by artificial means initially rice in temperature has positive impact but to an optimal level after that further increase in temperature will harm the rice yield. Fertilizer and water is having a positive and significant impact of the yield while technology has a positive but insignificant impact of the yield. Hence, the analysis suggests various possible initiatives and inclusive strategies to mitigate the adverse consequences of climatic fluctuations on productivity of crops, instead, enhance yield across regions of Pakistan. Supervisor:- Muhammad Aqeel Anwar